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It is specially formulated by experienced nutritionists with scientifically proven ingredients including Tryptophan, a natural precursor of serotonin, FOS, MOS and a unique probiotic to help maintain a healthy gut environment. We have more information about calmers for dogs in our information section.. Ideal for: Anxious and over-excitable dogs Travel anxiety Separation anxiety Fear of loud noises e.g. fireworks Improving focus and obedience Dogs with poor social skills