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Priligy (Dapoxetine) is the first non-topical treatment available for premature ejaculation. It comes as a tablet and is suitable for men aged from 18-64 who cannot regularly last longer than 2 minutes during sex. Dapoxetine belongs to a class of drugs known as “selective serotonin re-uptake inhibitors” (“SSRIs” for short). SSRI’s are usually used as anti-depressants. The difference between Priligy and traditional SSRIs is that Priligy works much quicker, giving your body a surge of serotonin when needed during sex and not long term, thus prolonging the heightened feeling during intercourse and making you last longer. How does Priligy Work? Priligy stops your body from “mopping up” serotonin, allowing for a prolonged heightened feeling during sex. This increased serotonin level also delays the ejaculation reflex signal. Making you last longer. Priligy comes in two strengths, 30mg and 60mg. It’s always recommended to start with the lower dose and treatment should be taken between 1 and 3 hours before sex. It’s not a daily treatment, rather a when required. Once taken, the treatment can last for up to four hours. Priligy and Erectile Dysfunction Treatments Priligy should not be taken alongside traditional PDE-5 inhibitor type (e.g. Viagra, Cialis, Sildenafil etc) treatments. This is because they can both cause a fall in blood pressure which can lead to dizziness and fainting. Use with more localised treatments such as Vitaros should be fine as Vitaros doesn’t cause the same marked reduction in blood pressure as its tablet counterparts. Priligy should be avoided with any medication that is likely to cause dizziness or drowsiness. Other Treatments Priligy is effective if the cause of premature ejaculation is not easy to get to the bottom of. If you know that you have certain lifestyle factors that could be causing it, then these should be controlled first (i.e. excessive alcohol consumption or drug use). Priligy should be taken for at least 6 doses to determine if Priligy is effective for you. Some men will need to use Priligy a few times where as others will find it effective from the 1st dose. If the cause is over sensitisation, then a topical numbing treatment like EMLA cream may also help. The use of extra thick condoms can also help prolong sexual activity. P.S. 2019