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Phenergan 25mg tablets are indicated: For short term use: To treat adults with difficulty sleeping insomnia To treat allergic conditions such as hay fever or rashes like nettle rash or hives To treat or stop you feeling sick nausea or being sick vomiting such as travel sickness For short term use: as a sedative for children aged 5 years and above How can the active ingredient promethazine hydrochloride help me The active ingredient in Phenergan is promethazine hydrochloride, which is an antihistamine that belongs to a group of medicines known as phenothiazines. When you have an allergic reaction, your body creates a natural substance called histamine. Histamine sends signals around your body that trigger symptoms of allergy, such as a runny nose or watery eyes. Antihistamines work by blocking histamine, which prevents your symptoms so you wont have to tolerate an allergic reaction. How long does Phenergan make you sleepy Promethazine the active ingredient in Phenergan will start to make you feel sleepy around 20 minutes after you take it and may work for up to 12 hours. If youre taking it for a cough or cold symptoms, allergies or nausea, your symptoms should start to improve within 20 minutes. The medicine should work for around 4 to 6 hours. Please take note of dosage requirements. Is Phenergan good for sleep Phenergan also works directly on the brain to help you feel more relaxed. Many people find Phenergan helps them when travelling with motion sickness. Phenergan Tablets are used to treat the following conditions: For short term use: to treat adults with difficulty sleeping insomnia. Pharmacist reviewed 10/19 Approved by Claire Makey - Pharmacist on the 12/04/2021. Ingredients What are the active ingredients Active ingredient: promethazine hydrochloride 25mg. Other ingredients: lactose, maize starch, povidone, magnesium stearate, polyethylene glycol, Opaspray contains titanium dioxide-E171, hypromelloseE464 and indigo carmine aluminium lake blue-E132 and hypromelloseIngredients Usage How to take Phenergan Tablets 25mg The recommended dose is: For allergies such as hay fever, rashes and hives Children 2-5 years : Phenergan Elixir should be given in this age group Children 5-10 years : A single tablet 25mg given at night DO NOT give more than 25mg each day Children over 10 years and adults including the elderly: Start with one tablet 25mg taken at night This may be increased to a maximum of one tablet 25mg twice a day if necessary For treatment and prevention of feeling sick or being sick such as travel sickness Children 2-5 years : Phenergan Elixir should be given in this age group Children 5-10 years : Phenergan Elixir or Phenergan 10mg Tablets should be given in this age group Children over 10 years and adults including the elderly: A single tablet 25 mg to be taken the night before the journey This may be repeated after 6-8 hours if necessary As a short term paediatric sedative and for short term treatment of insomnia in adults Children 2-5 years : Phenergan Elixir should be given in this age group Children 5-10 years : A single tablet 25mg given at night Children over 10 years and adults including the elderly: One or two tablets 25mg-50mg taken at night Use this medicine only as recommended. Do not exceed the recommended dose. Usage Warnings What are the precautions to conside before using/taking Phenergan Tablets 25mg Do not take this medicine if: The person taking the medicine is under 5 years of age You are allergic hypersensitive to promethazine hydrochloride or any of the other ingredients of Phenergan Tablets. The signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue. You are taking a medicine for depression called a monoamine oxidase inhibitor MAOI. Also do not take Phenergan Tablets if you have stopped taking one of these MAOI medicines within the last 14 days. If you are not sure ask your doctor or pharmacist The person is unconscious in a coma or suffers from severe dizziness, drowsiness or headache Do not take this medicine if any of the above applies to you. If you are not sure, talk to your doctor or pharmacist before taking Phenergan Tablets Check with your doctor or pharmacist before taking your medicine if: You have difficulty breathing, wheezing, tightness in the chest asthma or an infection in your lungs bronchitis You have epilepsy You have any serious heart problems You have liver or kidney problems You have a stomach blockage or difficulty passing water urine You have hearing problems You have increased pressure in the eye narrow angle glaucoma You have had something called Reyes Syndrome or possible Reyes Syndrome signs include being sick and confused following a viral illness If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Phenergan Tablets. Do not take this medicine, and tell your doctor, if you are taking or have taken the following in the last 2