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What are Co-codamol 8/500mg Tablets Co-codamol 8/500mg Tablets are used to help to relieve short-term acute, moderate pain, which is not relieved by paracetamol, ibuprofen or aspirin alone. Co-codamol 8/500 tablets can be used for the treatment of acute moderate pain such as headaches, migraine, neuralgia, toothache, dysmenorrhoea and rheumatic pain. This product contains paracetamol. DO NOT take any other paracetamol containing products with this medicine.